Evidence of concealed atrioventricular conduction in man.
نویسندگان
چکیده
THE TERM "concealed conduction" was introduced by Langendorfl to describe the phenomenon of entry of an electrical impulse into the A-V node without complete transmission but with modification of conduction of a subsequent impulse. This concept unified diverse observations of earlier years concerning disturbances of A-V transmission2-4 and clarified the mechanisms of many arrhythmias.5 6 Subsequent studies in animals have proved the occurrence of concealed conduction in the form of impulses which only partially penetrate the A-V nodal system.7 Most recently, Langendorf and his co-workers8 have conducted experiments in man which conclusively prove the occurrence of concealed conduction in patients with disease of the A-V conduction system. The present study became possible because 2:1 A-V conduction occurs in many healthy persons with normal A-V nodes when the right atrium is paced at rates only moderately above the intrinsic sinus nodal rate. This phenomenon permits observations of A-V nodal conduction time with and without an interposed atrial depolarization at comparable ventricular rates. The present experimental approach, which is a variant of that originally used by Lewis and Master,2 is applied here to the study of normal human A-V conduction.
منابع مشابه
Modulation of extracellular atrioventricular node field potential pattern and ventricular rhythm by morphine in experimental atrial fibrillation in isolated rabbit heart
Introduction: Endorphins are produced by cardiomyocytes, and exert different effects on the heart. The aim of the present study is to assess morphine effects on extracellular atrioventricular (AV) node field potential pattern and ventricular rhythm of isolated rabbit heart during experimental atrial fibrillation (AF). Methods: Effects of different concentrations of morphine (10, 20, 50 and 1...
متن کاملRe-entry due to manifest and concealed. His bundle ectopic systoles. Report of a case.
Concealed (C) His bundle ectopic systoles (H') have been shown in man to give rise to first and second degree atrioventricular (A-V) block and to simulate nonconducted atrial premature beats (P'). This report outlines a hitherto undescribed electrophysiologic consequence of H' in a 69-year-old man with arteriosclerotic heart disease and a Wenckebach type second degree A-V block in the His-Purki...
متن کاملFrequency-dependent electrophysiological properties of concealed slow pathway of isolated rabbit atrioventricular node preparation after fast pathway ablation in a functional model
Introduction: Intranodal pathways of atrioventricular (AV) node play a vital role in the delay of conduction time in response to various atrial inputs. The present study was aimed to determine the frequency-dependent electrophysiological properties of concealed slow pathway according to a functional model of isolated rabbit atrioventricular node preparation after fast pathway ablation. Meth...
متن کاملProtective effects of simvastatin on atrioventricular node during simulated experimental atrial fibrillation in vitro
Introduction: Recent evidence has indicated that statins can reduce the incidence of both supraventricular and ventricular arrhythmias with various mechanisms. The primary goal of the present study was to determine direct protective role of simvastatin in modifying concealed conduction and the zone of concealment in a simulated model of atrial fibrillation (AF) in an isolated atrioventricula...
متن کاملUnmasking of left free wall ventricular preexcitation by His bundle ablation.
His bundle ablation was performed in a 48 year old man with drug refractory orthodromic atrioventricular reentrant tachycardia and paroxysmal atrial fibrillation. Reentry was caused by a left free wall concealed accessory pathway. Interruption of the His bundle by low energy direct current shock (25 J) was quickly followed by anterograde conduction via the accessory pathway, with various forms ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Circulation
دوره 34 5 شماره
صفحات -
تاریخ انتشار 1966